Sunday, June 30, 2013

No, manufacturing jobs won?t revive the economy

In the American imagination, the phrases ?the decline of the middle class? and ?the loss of factory jobs? are almost inextricably linked. But the promise of a U.S. manufacturing revival has gained strength and currency in policy circles, with many arguing it?s a way to turn the economy around. President Obama has trumpeted the growth of factory jobs in speech after speech.??Think about the America within our reach,? he told his audience at last year?s State of the Union address. ?An America that attracts a new generation of high-tech manufacturing and high-paying jobs!?

But, for all the optimism and nostalgia for an America that once was, it?s worth asking whether factory jobs are more likely to help workers rise to the middle class today ? or leave them stranded among the working poor.

Elena Suarez was on her lunch break, taking a walk on the side of the road in the industrial park where she works, and eating a sandwich as she walked, when I stopped her to ask about her job. She?s a machine operator at Resonetics, a manufacturing company in Nashua, New Hampshire that specializes in precision laser micromachining for the medical device industry.

I asked Suarez how her job pays.

?Poor,? she said. ?I pay for working.?

Suarez commutes from Manchester, about half an hour away, and gas and car maintenance eat up quite a bit of her pay. She said she got the job through a staffing agency three years ago at a pay rate of $11 an hour. After two years, she was hired as a direct employee of the company, which meant she got a handful of paid sick days and access to medical and dental plans that cost a significant chunk of workers? paychecks. Her hourly pay also dropped to $10.50.

Her husband also works at a factory, but even with two incomes, the family has to budget carefully to get by. Suarez said she sees other families with more kids, or with only one working parent, and wonders how they manage.

?Sometimes I ask people, ?how do you do it??? she said. ?It?s not easy sometimes.?

Overall, even as the sophistication of manufacturing jobs has grown over the past 40 years, their pay has come nowhere near keeping pace with the growth in the economy as a whole. Adjusted for inflation, the average job in the industry now pays less than it did in the mid-1970s. If there are some high-skill factory jobs, there are also plenty of low-skill ones, filled, in many cases, by a rotating cast of temps or by people whose wages never rise above the temp level.

There are arguments for paying workers better. One was made by a 2012 Brookings Institute paper that argues the future of U.S. manufacturing depends on companies? willingness to take a ?high road? approach to production. That means investing in technology, using innovative methods and ensuring that workers have the skills to contribute to process improvements.

A second argument is a more fundamental one that applies to the economy as a whole: Workers are contributing to increasingly productive companies and ought to get a fair share of what they?re making.

The $1.2 billion international plastics molder Nypro is one company that embraces the notion of high-road manufacturing. Inside the old brick walls of a former carpet mill in Massachusetts, sophisticated plastic extruding machines turn out machinery for fixing human bodies. The plant makes components for medical devices, and it requires significant sophistication from its workers. Even many floor-level production workers need to understand computers and robots and industry quality standards.

?It?s very unusual to find somebody who?s been out here for two years with less than a two-year college education level,? said company spokesman Al Cotton.

Workers come in with less education, he said, but they?re put into classes at ?Nypro University? before or after their work shifts, mostly at the company?s expense, and some go as far as a master?s degree from local colleges that have affiliation agreements with the training program. Some workers handling advanced, computer-driven machines can make more than $100,000 a year, Cotton said, although that?s partly because there?s such a shortage of people who can fill these positions that they end up working 60 hours a week.

Nypro is growing. When I talked to Cotton in late May, the company was looking to fill 100 positions at the Massachusetts location.

Atrium Medical in Hudson, New Hampshire is another growing plastics company in the medical device industry, but, at least according to some of its workers, it puts less focus on investing in its employees. (Officials at the company didn?t return my calls, which was also the case with Resonetics.)

Atrium was acquired by Maquet Getinge Group of Sweden in 2011 for $680 million, and it has plans to move to a larger building soon. When I stopped by the plant on a sunny afternoon, workers were outside, eating lunch at picnic tables. I approached two women speaking with each other quietly in Spanish and asked about their jobs. They?re assemblers, they said. When I asked if the jobs are good ones, they hesitated.

?They pay the minimum,? one said. ?Like $8 an hour.?

That?s the starting pay, she added. She and her friend have been working here for 10 years. How much do they make now? $9 an hour.

Another woman, eating lunch in her car, told me the assemblers move between standing and sitting. ?We do everything by hand,? she said, except ?the guys,? who run welding machines. ?If you can?t keep up, watch it,? she said.

?We don?t get paid much, let me put it that way,? she added. ?For the work we do, we don?t get paid much.?

When I approached another worker, a machine operator named Julio Abreu, he immediately told me ?I love this place.?

The benefits aren?t the best, he said, but, after two years on the job, he recently got a $1 raise to $11 an hour. Since his girlfriend makes a similar wage they?re able to support their son. And he likes the schedule, working 10-hour days Monday through Thursday and getting Fridays off. When I asked him if he?d like to stay at the job, though, he laughed and said it?s good enough until he can go back to college. With a slight edge of sarcasm, he added ?It?s not my dream job.?

The differences between Nypro and Atrium aren?t black and white. Ten to 15 percent of the production workers at Nypro?s Massachusetts plant are temps making as little as $10 an hour, and there are certainly some highly technical, well-paid jobs at Atrium, but the two companies begin to give a sense of how varied production jobs are.

If you want to really see how all-over-the-map manufacturing jobs can be, look no further than Craigslist. In Michigan, one of the states where the industry?s employment has been growing quickly, jobs promising $35 an hour plus benefits for running computer-operated lathes sit alongside ones like this: ?We are looking for candidates with at least one year of manufacturing experience. Candidates must be able to lift 50lbs and bend, twist, and stand all day long. All candidates must be flexible in shifts and available to work overtime and weekends when required?. Compensation: $8.00/hr.?

The current moment is an interesting one for manufacturing. The industry did a spectacular nose-dive between 2006 and 2010, losing more than 2.5 million jobs and hitting a historic low of less than 11.5 million. After that, it began a slight upswing, rising to nearly 12 million. There is much debate among economists about whether that growth will continue, but advocates, including President Obama, have begun a push to help make it happen. Obama has created several pilot programs to help companies adopt high-tech manufacturing processes and to get workers trained to participate in them.

And yet, for all the talk of good jobs in an increasingly high-tech industry, as manufacturing employment has begun to grow, pay in the industry hasn?t gone up. In real terms, the median hourly wage for production workers in manufacturing?which includes front-line supervisors and programmers of computer-controlled machinery as well as hand assemblers and meatpackers?fell from $15.87 in 2010 to $15.51 in 2012, according to the Bureau of Labor Statistics. Those numbers are probably a bit high, since they don?t include temps.

On average, factory workers with little education still make a bit more than they might in retail or fast food, but that?s by no means always true. And, unlike service-sector employers, manufacturing plants are almost worshipped by American politicians. It?s hard to find a plant that expands or opens a new location without getting some sort of tax subsidy. Resonetics got a government-supported financing package when it opened its plant in Nashua, and when Atrium moves to its new location, it will be eligible for a New Hampshire state tax incentive.

Howard Wial, one of the authors of the Brookings Institute paper that advocates high-road manufacturing, said some state and local incentives do require that companies pay a certain wage, but they?re not common, and even when they exist there?s often no enforcement mechanism. In general, he said, the incentives are not particularly connected to creating good jobs.

?They?re just about poaching jobs from one place to another without creating any new value,? he said.

Wial, who is the head of the University of Illinois at Chicago?s Center for Urban Economic Development, said Obama?s efforts to encourage high tech manufacturing growth would also be stronger if they encouraged companies to pay well and supported unionization. Even without that, though, he said the federal programs are one way of helping manufacturers to be smart about their approach to technology. Right now, he said, technical sophistication varies dramatically from plant to plant.

?Some companies have thought very hard about how best to organize work and how to make the best use of workers? skills, how to use more skilled workers, how to involve workers in making decisions that are important for improving production and innovating,? he said. ?And some companies don?t really think very systematically about this at all.?

The difference, he said, means some companies are far more productive?and internationally competitive?than others. And, he said, there?s generally a correlation between the more productive companies and the pay levels of their workers.

?Certainly there are high-productivity companies where the workers don?t share in the benefits,? he said, ?But, in general, to reach the highest levels of productivity, you need to have workers actively involved in solving problems, and they?re not going to be willing and able to do that if they don?t share in the benefits.?

Among the report?s findings are that manufacturing wages are on the low end in the U.S. compared with other industrialized countries, and yet the nation lost more jobs between 2000 and 2010 than higher-paying countries. The study also found that even within one narrow category of workers?automotive stampers who use stamping presses to make car parts from sheet metal?U.S. wages ranged from $10 to $17 an hour.

Aside from the conclusion that high wages go along with higher productivity, the report also notes that direct labor costs typically make up ?far less than 20 percent? of a manufacturer?s total costs, making pay level a relatively unimportant factor in competitiveness.

?Overall, manufacturing is not nearly as labor-intensive as it once was, so it?s mattering less,? Wial said.

And yet, he added, that doesn?t mean companies are being particularly generous when it comes to wages.

?Over time we?ve seen this very disturbing trend of, we?ve had productivity growth and the typical worker hasn?t shared in that very much, if at all.?

Steve Sawin is one of the people who believes in a manufacturing resurgence. An old-school American businessman dressed neatly in shirt and tie and well-shined shoes, he sees high-profile companies like GE rethinking their processes and finding that it just makes more sense to make many products in the U.S. than overseas.

?Manufacturing built the middle class of this country,? he said. ?We need to rebuild that manufacturing base to rebuild our middle class.?

Sawin is the CEO of Operon, a company that, he says, is not a temp agency. It provides medical device companies, including both Nypro and Atrium, not just warm bodies to run machines and assemble parts but people who?ve been chosen for their ability to work in modern manufacturing settings and then trained for the specific companies where they?ll be working.

At Nypro, Sawin and Amy Oskirko, an Operon area manager, have a workspace set up in a corner of the factory, defined by temporary partitions enclosing several large tables. There, applicants?20 to 40 of them a week for Nypro alone?take tests in reading comprehension, basic math, manual dexterity and vision. If they do well, they move on to get trained in industry standards for documentation, use of calipers and microscopes for inspecting plastic parts and how to ?gown and degown??dressing in hygienic plastic from hair net to shoe coverings to keep the products clean. The entire process takes 6 ? to 8 ? hours over two days?unpaid?depending on the client company?s training needs, Oskirko said.

Sawin said his company offers services that help U.S. companies compete. With employees that work for Operon, they can easily add or subtract workers based on their needs at any given moment, and they can hire the ones that work out best as permanent employees. His company helps take the guesswork out of labor, the most variable component in any production process.

?You go out and buy a bag of screws, you?re confident they?re all going to work with very little exceptions,? he said. ?People on the other hand? they are all over the map.?

For the most part, Sawin said, the positions he?s filling aren?t complex, thanks partly to the automation of production functions.

?It has relegated the human role in many cases to inspecting, monitoring and controlling machines, packaging, labeling and maybe a little assembly,? he said.

Along with all the other training topics, new recruits watch a DVD labeled ?work ethic.? Sawin said it?s something you can?t really teach, but they try because it?s a big issue among the people they hire?the biggest reason they don?t get hired on full-time.

?For some reason a lot of young people have not been indoctrinated in the basic tenet of the good work ethic,? he said.

Sawin said the pay rate for the people he hires is between $9 and $12 an hour. Operon doesn?t offer health insurance?the plans it wanted to provide didn?t meet state-mandated minimums in Massachusetts or New Hampshire.

Even if the pay were only $8, a level that?s not uncommon for temps in the industry, Sawin said that?s not bad considering that the work is entry level.

?This guy could have been bagging groceries at Stop & Shop last week,? he said.

I asked Sawin if people might work harder if they were paid more, but they said he doesn?t think so.

?I don?t think it has to do with pay as much as it does with principles,? he said.

If there?s debate over whether paying production workers more increases productivity, there is also that other argument to consider.? How much does a worker contribute to a company?s success, and what kind of compensation does she deserve for her work? Companies are quite unlikely to pose this question to themselves. Raising it has, historically, been the job of the labor movement.

But few workers in manufacturing today are represented by unions?13.4 percent of production workers in 2012, down from 19.2 percent as recently as 2002.

?It?s become almost impossible to form a union through the National Labor Relations Act procedures nowadays,? said Brad Markell, executive director of the AFL-CIO Industrial Union Council.

When it comes to a real resurgence in manufacturing, Markell is skeptical that there will be much progress unless the U.S. revises its trade policies, but he said there?s no inherent reason why the production jobs that do exist in the country now don?t pay better than they do.

?The value added per employee in those areas is enough to support a well-paying job, but the question is whether the workers have the power to extract the pay from those companies,? he said. ?In an era of high unemployment, and when we?ve lost a lot of manufacturing jobs, and when people aren?t joined together in a union it?s very hard.?

Markell said it?s also not clear that more complicated products and processes in manufacturing lead to jobs that demand better training, or command better pay.

?The average 17-year-old is extremely sophisticated on computers, so how much education does it take?? he said. ?It?s certainly not the case that because jobs involve computers that they pay better. It?s more about the power dynamic.?

Resonetics, the laser micromachining company where Elena Suarez works, is a high-tech manufacturer by almost any measure. Its machines can features as small as a thousandth of a millimeter, and it does this for the medical device industry, a sector that is obsessively interested in new technology. But when I asked Suarez if the job took much training she shrugged and said, well, you have to learn to use the machines.

One of Suarez?s coworkers, who asked me to refer to her only as Judy, said running the machines isn?t particularly hard. ?If anything it?s more boring than demanding,? she said.

Judy, a woman with a look and manner that suggest an office manager more than a machine operator, has been in manufacturing for 30 years. She spent most of that time at a company that makes electronic testing equipment. She trained there as a computer programmer and went back to school for blueprint reading. Over time she brought her pay up to $20 an hour. But when that company closed the local plant, she found her skills didn?t translate. When she was hired at Resonetics four years ago, her experience won her a starting wage of $12.50 an hour. Soon she learned new skills, including inspection, which means staring into a microscope looking for flaws in the plastic products the machines produce?it?s harder on the shoulders and neck than on the eyes, she told me. Today her pay is up to $15 an hour.

She?s able to live on that, she said, partly because she paid off her mortgage over her years at the higher paying job. It also helps that she?s getting a pension from that job.

Judy said management seems to have improved at Resonetics since she started there, but in general she thinks the industry is tougher for workers than it once was.

?I think years ago loyalty played a role in it,? she said. ?That?s not the case anymore. It?s all about the money. The bottom line for the people who own the business is ?how can I make the most money by expending the least money???

Source: http://www.salon.com/2013/06/29/no_manufacturing_jobs_wont_revive_the_economy/

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Buckley Dark week in Boston sports

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    'The Heat' hot at box office but 'Monsters' rule

    This publicity photo released by Twentieth Century Fox shows Sandra Bullock, left, as FBI Special Agent Sarah Ashburn, and Melissa McCarthy, as Boston Detective Shannon Mullins, in a scene from the film, "The Heat." The movie releases June 28, 2013. (AP Photo/Twentieth Century Fox, Gemma La Mana)

    This publicity photo released by Twentieth Century Fox shows Sandra Bullock, left, as FBI Special Agent Sarah Ashburn, and Melissa McCarthy, as Boston Detective Shannon Mullins, in a scene from the film, "The Heat." The movie releases June 28, 2013. (AP Photo/Twentieth Century Fox, Gemma La Mana)

    This publicity photo released by Twentieth Century Fox shows Melissa McCarthy, left, as Detective Shannon Mullins, and Sandra Bullock as FBI Special Agent Sarah Ashburn, in a scene from the film, "The Heat." The movie releases June 28, 2013. (AP Photo/Twentieth Century Fox, Gemma La Mana)

    This film publicity image released by Disney-Pixar shows a scene from "Monsters University." (AP Photo/Disney-Pixar)

    This film publicity image released by Disney-Pixar shows a scene from "Monsters University." (AP Photo/Disney-Pixar)

    (AP) ? Sandra Bullock and Melissa McCarthy brought "The Heat" against Channing Tatum and Jamie Foxx at the box office.

    The Fox action-comedy starring the funny ladies as mismatched detectives earned $40 million in second place in its opening weekend, topping the $25.7 million debut haul of Sony's "White House Down," according to studio estimates Sunday.

    The Disney-Pixar animated prequel "Monsters University" remained box-office valedictorian in its second weekend, earning $46.1 million in first place.

    As for "The Heat," employing two female leads to buck the male-dominated buddy-cop formula paid off in ticket sales.

    "I think the fact that we have a female-centric movie standing out in a forest of giant tent-pole movies is phenomenal," said Chris Aronson, Fox's president of domestic distribution. "Audiences really responded. We positioned this to be a female event movie, and we got the opening that we were hoping for this weekend."

    "White House Down," which features Tatum as a wannabe Secret Service agent and Foxx as the President of the United States of America, was inaugurated below expectations in fourth place. The film's White House takeover plot is strikingly similar to FilmDistrict's "Olympus Has Fallen," which opened in March and starred Gerard Butler and Aaron Eckhart.

    "It turned out to be a very competitive weekend," said Rory Bruer, Sony's president of worldwide distribution. "We had hoped 'White House Down' did better, just from the standpoint that we love this film, but I feel very hopeful that with the July 4th holiday coming up, it will be the perfect film for audiences, and it'll really add up for us."

    Meanwhile, Paramount's "World War Z" took another bite out of the box office in its second weekend domestically with $29.8 million. Overseas, the globe-trotting zombie thriller starring Brad Pitt cleared $70.1 million in 51 territories.

    "I think the variety of films is what brought people out to the movie theaters," said Paul Dergarabedian, an analyst for box-office tracker Hollywood.com. "There's a G-rated movie at the top of the chart and an R-rated movie in second place. That says a lot about the summer marketplace and how a unique slate of films can propel the box office."

    "Man of Steel" is still flying high in its third week, coming in fifth place with $20.8 million in North America and $52.2 million in such international markets as Australia, Sweden and China. The Warner Bros. retelling of Superman's origin passed the $500 million mark on Saturday.

    Overall, Dergarabedian said revenue and attendance are now both down just 2 percent over last year, and this weekend's films grossed 8.5 percent less than last year when Universal's "Ted" opened with $54.4 million at the box office. He said those numbers could shift further next week when Disney's "The Lone Ranger" and Universal's "Despicable Me 2" debut.

    ___

    Estimated ticket sales for Friday through Sunday at U.S. and Canadian theaters, according to Hollywood.com. Where available, latest international numbers are also included. Final domestic figures will be released on Monday.

    1. "Monsters University," $46.1 million ($44.2 million international).

    2. "The Heat," $40 million.

    3. "World War Z," $29.8 million ($70.1 million international).

    4. "White House Down," $25.7 million ($6.8 million international.)

    5. "Man of Steel," $20.8 million ($52.2 million international).

    6. "This Is the End," $8.7 million.

    7. "Now You See Me," $5.5 million ($5 million international).

    8. "Fast & Furious 6," $2.4 million ($6.1 million international).

    9. "Star Trek: Into Darkness," $2 million ($2 million international).

    10. "The Internship," $1.4 million ($3.6 million international).

    ___

    Estimated weekend ticket sales at international theaters (excluding the U.S. and Canada) for films distributed overseas by Hollywood studios, according to Rentrak:

    1. "World War Z," $70.1 million.

    2. "Man of Steel," $52.2 million.

    3. "Monsters University," $44.2 million.

    4. "Despicable Me 2," $41.5 million.

    5. "The Hangover Part III," $7.7 million.

    6. "Fast & Furious 6," $6.1 million.

    7. "Epic," $5.1 million.

    8. "Now You See Me," $5 million.

    9. "The Internship," $3.6 million.

    10. "The Great Gatsby," $3.3 million.

    ___

    Universal and Focus are owned by NBC Universal, a unit of Comcast Corp.; Sony, Columbia, Sony Screen Gems and Sony Pictures Classics are units of Sony Corp.; Paramount is owned by Viacom Inc.; Disney, Pixar and Marvel are owned by The Walt Disney Co.; Miramax is owned by Filmyard Holdings LLC; 20th Century Fox and Fox Searchlight are owned by News Corp.; Warner Bros. and New Line are units of Time Warner Inc.; MGM is owned by a group of former creditors including Highland Capital, Anchorage Advisors and Carl Icahn; Lionsgate is owned by Lions Gate Entertainment Corp.; IFC is owned by AMC Networks Inc.; Rogue is owned by Relativity Media LLC.

    ___

    Follow AP Entertainment Writer Derrik J. Lang on Twitter at http://www.twitter.com/derrikjlang.

    Associated Press

    Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2013-06-30-Box%20Office/id-9c84fbde585a46caa6e042b272c59662

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    Saturday, June 29, 2013

    Scientists view 'protein origami' to help understand, prevent certain diseases

    June 28, 2013 ? Scientists using sophisticated imaging techniques have observed a molecular protein folding process that may help medical researchers understand and treat diseases such as Alzheimer's, Lou Gehrig's and cancer.

    The study, reported this month in the journal Cell, verifies a process that scientists knew existed but with a mechanism they had never been able to observe, according to Dr. Hays Rye, Texas A&M AgriLife Research biochemist.

    "This is a step in the direction of understanding how to modulate systems to prevent diseases like Alzheimer's. We needed to understand the cell's folding machines and how they interact with each other in a complicated network," said Rye, who also is associate professor of biochemistry and biophysics at Texas A&M.

    Rye explained that individual amino acids get linked together like beads on a string as a protein is made in the cell.

    "But that linear sequence of amino acids is not functional," he explained. "It's like an origami structure that has to fold up into a three-dimensional shape to do what it has to do."

    Rye said researchers have been trying to understand this process for more than 50 years, but in a living cell the process is complicated by the presence of many proteins in a concentrated environment.

    "The constraints on getting that protein to fold up into a good 'origami' structure are a lot more demanding," he said. "So, there are special protein machines, known as molecular chaperones, in the cell that help proteins fold."

    But how the molecular chaperones help protein fold when it isn't folding well by itself has been the nagging question for researchers.

    "Molecular chaperones are like little machines, because they have levers and gears and power sources. They go through turning over cycles and just sort of buzz along inside a cell, driving a protein folding reaction every few seconds," Rye said.

    The many chemical reactions that are essential to life rely on the exact three-dimensional shape of folded proteins, he said. In the cell, enzymes, for example, are specialized proteins that help speed biological processes along by binding molecules and bringing them together in just the right way.

    "They are bound together like a three-dimensional jigsaw puzzle," Rye explained. "And the proteins -- those little beads on the string that are designed to fold up like origami -- are folded to position all these beads in three-dimensional space to perfectly wrap around those molecules and do those chemical reactions.

    "If that doesn't happen -- if the protein doesn't get folded up right -- the chemical reaction can't be done. And if it's essential, the cell dies because it can't convert food into power needed to build the other structures in the cell that are needed. Chemical reactions are the structural underpinning of how cells are put together, and all of that depends on the proteins being folded in the right way."

    When a protein doesn't fold or folds incorrectly it turns into an "aggregate," which Rye described as "white goo that looks kind of like a mayonnaise, like crud in the test tube.

    "You're dead; the cell dies," he said.

    Over the past 20 years, he said, researchers have linked that aggregation process "pretty convincingly" to the development of diseases -- Alzheimer's disease, Lou Gehrig's disease, Huntington's disease, to name a few. There's evidence that diabetes and cancer also are linked to protein folding disorders.

    "One of the main roles for the molecular chaperones is preventing those protein misfolding events that lead to aggregation and not letting a cell get poisoned by badly folded or aggregated proteins," he said.

    Rye's team focused on a key molecular chaperone -- the HSP60.

    "They're called HSP for 'heat shock protein' because when the cell is stressed with heat, the proteins get unstable and start to fall apart and unfold," Rye said. "The cell is built to respond by making more of the chaperones to try and fix the problem.

    "This particular chaperone takes unfolded protein and goes through a chemical reaction to bind the unfolded protein and literally puts it inside a little 'box,'" Rye said.

    He added that the mystery had long been how the folding worked because, while researchers could see evidence of that happening, no one had ever seen precisely how it happened.

    Rye and the team zeroed in on a chemically modified mutant that in other experiments had seemed to stall at an important step in the process that the "machine" goes through to start the folding action. This clued the researchers that this stalling might make it easier to watch.

    They then used cryo-electron microscopy to capture hundreds of thousands of images of the process at very high resolutions which allowed them to reconstruct from two-dimensional flat images a three-dimensional model. A highly sophisticated computer algorithm aligns the images and classifies them in subcategories.

    "If you have enough of them you can actually reconstruct and view a structure as a three-dimensional model," Rye said.

    What the team saw was this: The HSP60 chaperone is designed to recognize proteins that are not folded from the ones that are. It binds them and then has a separate co-chaperone that puts a "lid" on top of the box to keep the folding intermediate in the box. They could see the box move, and parts of the molecule moved to peel the chaperone box away from the bound protein -- or "gift" in the box. But the bound protein was kept inside the package where it could then initiate a folding reaction. They saw tiny tentacles, "like a little octopus in the bottom of the box rising up and grabbing hold of the substrate protein and helping hold it inside the cavity."

    "The first thing we saw was a large amount of an unfolded protein inside of this cavity," he said. "Even though we knew from lots and lots of other studies that it had to go in there, nobody had ever seen it like this before. We can also see the non-native protein interacting with parts of the box that no one had ever seen before. It was exciting to see all of this for the first time. I think we got a glimpse of a protein in the process of folding, which we actually can compare to other structures."

    "By understanding the mechanism of these machines, the hope is that one of the things we can learn to do is turn them up or turn them off when we need to, like for a patient who has one of the protein folding diseases," he said.

    Rye collaborated on the research with Dong-Hua Chen and Wah Chiu at the Baylor College of Medicine in Houston, Damian Madan and Zohn Lin at Princeton University, Jeremy Weaver at Texas A&M and Gunnar Schr?der at the Institute of Complex Systems in Germany.

    Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/PfjFPU7j0xE/130628120759.htm

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    Facebook Announces New Review Policy To Prevent Ads From Running On Controversial Pages And Groups

    facebook adsFacebook just announced a new review policy for Pages and Groups, a policy aimed at reducing cases where ads run alongside content that the advertiser or their customers might find objectionable. Earlier today, a BBC report stated that Marks and Spencer and BSkyB had pulled "all or part of their spending" on Facebook after a BSkyB ad (which was "promoting an M&S voucher") was shown alongside a Facebook Page that was titled "cute and gay boys" and included photos of teenage boys. The story said Facebook was going to make an announcement to address these types of concerns later today.

    Source: http://feedproxy.google.com/~r/Techcrunch/~3/BCQG_UlPC8k/

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    Obama says managing Afghanistan exit is a priority

    Four people who were on the ground the night of the Benghazi attacks last year are writing a book about their experience, and they're getting a $3 million advance from Twelve Books to do it. The authors are unnamed, according to New York Post's Keith J. Kelly, who describes them as "members of the elite security team from the annex of the US Embassy." That annex, we now know, was the CIA annex, which makes this book deal really fascinating. ...

    Source: http://news.yahoo.com/obama-says-managing-afghanistan-exit-priority-111250278.html

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    Pump prices keep falling; oil drops below $97

    (AP) ? As the week went along, Americans' commutes got cheaper.

    The average price for a gallon of gasoline fell by 6 cents from Monday through Friday, to a two-month low of $3.51 per gallon. The average fell at least a penny in 48 states, with only Hawaii prices gaining a fraction and Idaho's staying flat. The steepest declines were in Indiana (15 cents) and Michigan (14 cents).

    A number of refineries that suffered outages in the Midwest in the past month or so returned to operation, easing a shortage of gasoline and dropping prices. The average price has fallen 40 cents in both Michigan and Wisconsin since June 1.

    Meanwhile, the price of oil fell Friday for the first time this week, and it finished the second quarter of the year with a slight loss.

    Benchmark oil for August delivery fell 49 cents to end at $96.56 per barrel on the New York Mercantile Exchange. For the April-June quarter, oil slipped 67 cents, although it rose 11 percent from a low of $86.68 on April 17.

    The decline at the gas pump is good news for drivers as the July Fourth holiday approaches. Most should pay less than on Memorial Day, when gas averaged about $3.65. But this year's June swoon isn't as large as last year's ? by Independence Day in 2012, the average price was $3.34.

    Brent crude, which is used to set prices for oil used by many U.S. refineries to make gasoline, fell 66 cents to $102.16 a barrel.

    In other energy futures trading on the Nymex:

    ? Heating oil fell 1 cent to $2.88 a gallon.

    ? Natural gas fell 2 cents to $3.57 per 1,000 cubic feet.

    ? Wholesale gasoline rose 1 cent to $2.75 a gallon.

    Associated Press

    Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2013-06-28-Oil%20Prices/id-1a342b2742624b8a82f12fa3655b42b7

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    What Are The Asbestos Risks After a Recent Warehouse Fire ...

    Residents on Belmont Ave. were greeted by clouds of thick smoke rising over their neighborhood on Saturday. A warehouse had gone up in flames over the weekend, but there?s something beyond the fire that is posing a serious risk to those living nearby.

    Paper debris from the fire floated across the area, scattering dangerous pieces of the toxic material asbestos. Fine asbestos fibers can easily be inhaled and become trapped in the lungs. Overtime this can cause serious health issues like asbestosis, which causes breathing difficulties, and mesothelioma, a rare and deadly form of lung cancer.

    And these risks are very real for the people near the Belmont fire. The owner of the building where the fire began was ordered by the Marion County Health Department to hire cleaning crews, who quickly arrived on the scene to remove the dangerous materials. The EPA even brought in their own members to help out as well. The public has been warned to not touch the toxic materials and to avoid cutting their grass as it could release dangerous fibers into the air. They have also been advised to wet down any debris and to not use their bare hands if picking it up.

    According to a clean-up coordinator, ?It?s mainly in big chunks now and we?re trying to prevent it from breaking up and getting into the small pieces that people can inhale.? They?re also monitoring the air as they go to make sure no asbestos fibers have gone airborne. Crews will continue to clean throughout the nearby neighborhoods until the asbestos threat is completely removed. The cause of the original fire, however, still isn?t known.

    Indiana asbestos exposure lawyer

    Personal Injury Lawyers in Indianapolis

    Asbestos exposure is incredibly dangerous and sometimes it takes symptoms of asbestos-related illnesses years to show up. If you?ve been exposed to asbestos at work or in your community and suffered complications, you should contact the Indianapolis injury lawyers at the Ken Nunn Law Office.

    We may be able to help you receive compensation that will help cover the expensive costs of dealing with a serious asbestos-related illness. Contact us today and let us tell you how we can help.

    Source. TheIndyChannel.com, ?http://www.theindychannel.com/news/local-news/workers-clean-up-asbestos-debris-in-neighborhoods-near-warehouse,? Chris Proffitt, June 23, 2013.
    Source. WTHR.com, ?http://www.wthr.com/story/22665781/2013/06/23/asbestos-cleanup-begins-after-belmont-fire,? Carrie Cline, June 23, 2013.

    Source: http://kennunn.com/blog/what-are-the-asbestos-risks-after-a-recent-warehouse-fire-indianapolis-personal-injury-lawyers/

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    Thursday, June 27, 2013

    Turning off cells in habit-associated brain region prevents rats from learning to run maze on autopilot

    June 27, 2013 ? Our daily routines can become so ingrained that we perform them automatically, such as taking the same route to work every day. Some behaviors, such as smoking or biting your fingernails, become so habitual that we can't stop even if we want to.

    Although breaking habits can be hard, MIT neuroscientists have now shown that they can prevent them from taking root in the first place, in rats learning to run a maze to earn a reward. The researchers first demonstrated that activity in two distinct brain regions is necessary in order for habits to crystallize. Then, they were able to block habits from forming by interfering with activity in one of the brain regions -- the infralimbic (IL) cortex, which is located in the prefrontal cortex.

    The MIT researchers, led by Institute Professor Ann Graybiel, used a technique called optogenetics to block activity in the IL cortex. This allowed them to control cells of the IL cortex using light. When the cells were turned off during every maze training run, the rats still learned to run the maze correctly, but when the reward was made to taste bad, they stopped, showing that a habit had not formed. If it had, they would keep going back by habit.

    "It's usually so difficult to break a habit," Graybiel says. "It's also difficult to have a habit not form when you get a reward for what you're doing. But with this manipulation, it's absolutely easy. You just turn the light on, and bingo."

    Graybiel, a member of MIT's McGovern Institute for Brain Research, is the senior author of a paper describing the findings in the June 27 issue of the journal Neuron. Kyle Smith, a former MIT postdoc who is now an assistant professor at Dartmouth College, is the paper's lead author.

    Patterns of habitual behavior

    Previous studies of how habits are formed and controlled have implicated the IL cortex as well as the striatum, a part of the brain related to addiction and repetitive behavioral problems, as well as normal functions such as decision-making, planning and response to reward. It is believed that the motor patterns needed to execute a habitual behavior are stored in the striatum and its circuits.

    Recent studies from Graybiel's lab have shown that disrupting activity in the IL cortex can block the expression of habits that have already been learned and stored in the striatum. Last year, Smith and Graybiel found that the IL cortex appears to decide which of two previously learned habits will be expressed.

    "We have evidence that these two areas are important for habits, but they're not connected at all, and no one has much of an idea of what the cells are doing as a habit is formed, as the habit is lost, and as a new habit takes over," Smith says.

    To investigate that, Smith recorded activity in cells of the IL cortex as rats learned to run a maze. He found activity patterns very similar to those that appear in the striatum during habit formation. Several years ago, Graybiel found that a distinctive "task-bracketing" pattern develops when habits are formed. This means that the cells are very active when the animal begins its run through the maze, are quiet during the run, and then fire up again when the task is finished.

    This kind of pattern "chunks" habits into a large unit that the brain can simply turn on when the habitual behavior is triggered, without having to think about each individual action that goes into the habitual behavior.

    The researchers found that this pattern took longer to appear in the IL cortex than in the striatum, and it was also less permanent. Unlike the pattern in the striatum, which remains stored even when a habit is broken, the IL cortex pattern appears and disappears as habits are formed and broken. This was the clue that the IL cortex, not the striatum, was tracking the development of the habit.

    Multiple layers of control

    The researchers' ability to optogenetically block the formation of new habits suggests that the IL cortex not only exerts real-time control over habits and compulsions, but is also needed for habits to form in the first place.

    "The previous idea was that the habits were stored in the sensorimotor system and this cortical area was just selecting the habit to be expressed. Now we think it's a more fundamental contribution to habits, that the IL cortex is more actively making this happen," Smith says.

    This arrangement offers multiple layers of control over habitual behavior, which could be advantageous in reining in automatic behavior, Graybiel says. It is also possible that the IL cortex is contributing specific pieces of the habitual behavior, in addition to exerting control over whether it occurs, according to the researchers. They are now trying to determine whether the IL cortex and the striatum are communicating with and influencing each other, or simply acting in parallel.

    "A role for the IL cortex in the regulation of habit is not a new idea, but the details of the interaction between it and the striatum that emerge from this analysis are novel and interesting," says Christopher Pittenger, an assistant professor of psychiatry and psychology at Yale University School of Medicine, who was not part of the research team. "Thinking in the long term, it raises the question of whether targeted manipulations of the IL cortex might be useful for the breaking habits -- and exciting possibility with potential clinical ramifications."

    The study suggests a new way to look for abnormal activity that might cause disorders of repetitive behavior, Smith says. Now that the researchers have identified the neural signature of a normal habit, they can look for signs of habitual behavior that is learned too quickly or becomes too rigid. Finding such a signature could allow scientists to develop new ways to treat disorders of repetitive behavior by using deep brain stimulation, which uses electronic impulses delivered by a pacemaker to suppress abnormal brain activity.

    The research was funded by the National Institutes of Health, the Office of Naval Research, the Stanley H. and Sheila G. Sydney Fund and funding from R. Pourian and Julia Madadi.

    Source: http://feeds.sciencedaily.com/~r/sciencedaily/living_well/~3/6fOZ1dlBvr8/130627125522.htm

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    Around the Web?

    Happy hump day! Wednesday’s links are just waiting for you to give them a click: Six-year-old transgender girl wins the right to use the ladies room at her elementary school — ABC News How to keep your kids safe around the pool this summer — Breezy Mama New study: breastfed babies have a higher social […]

    Source: http://feeds.celebritybabies.com/~r/celebrity-babies/~3/qcYQLa7WouQ/

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    Wednesday, June 26, 2013

    Spain denies robbery was linked to team party

    FORTALEZA, Brazil (AP) ? Spain has acknowledged six of its players were robbed during the first week of the Confederations Cup, but is denying the theft took place at a team party.

    The Spanish Football Federation, which had previously declined to give specifics, issued a statement on Tuesday responding to reports in the Brazilian media that the theft was connected to a team party following a 2-1 victory over Uruguay in Recife nine days ago.

    The federation "categorically denies" the reports and called the allegations damaging to "the honor of the players and their family and friends."

    Brazilian media, citing employees of the hotel and security officials, reported that women from outside the Spanish traveling party and alcohol were involved in the party at the team hotel.

    The Spanish federation said that "Six national team players were the subject of a robbery at the team's hotel in Recife during the stay for the game between Spain and Uruguay in the Confederations Cup. This was reported in a timely manner to the Brazilian police.

    "This statement is not an attack against the organizing committee, nor against FIFA, nor the country of Brazil, which has welcomed the Spanish team. An event like this could take place anywhere in the world, including Spain.

    "Since then, a series of verbal attacks on our players has been published, which the RFEF totally rejects and profoundly condemns. They damage the honor of the players and their family and friends."

    The statement ended by saying the aim of the reports was to "cause harm to the good name of the players on the team, who have demonstrated good conduct, professionalism and exemplary behavior for many years."

    Defender Gerard Pique, one the players reported by Brazilian media to have been involved, called the reports "a total lie."

    Spain faces Italy on Thursday in the Confederations Cup semifinals, looking to reach the final on Sunday and win the only major tournament title it lacks. Spain won the 2010 World Cup and the last two European championships.

    Security has long been a problem in Brazil, where muggings, carjackings and armed robberies are common. It's a concern leading up to the 2014 World Cup and the 2016 Olympics in Rio de Janeiro.

    Last Wednesday, the wife of Brazil goalkeeper Julio Cesar said she was robbed at gunpoint in Fortaleza, where Brazil played Mexico that day. In the capital Brasilia, the hotel room of at least one journalist was robbed before the opening match of the Confederations Cup.

    Source: http://news.yahoo.com/spain-denies-robbery-linked-team-party-125955098.html

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    Two mutations triggered an evolutionary leap 500 million years ago

    June 24, 2013 ? Evolution, it seems, sometimes jumps instead of crawls. A research team led by a University of Chicago scientist has discovered two key mutations that sparked a hormonal revolution 500 million years ago.

    In a feat of "molecular time travel," the researchers resurrected and analyzed the functions of the ancestors of genes that play key roles in modern human reproduction, development, immunity and cancer. By re-creating the same DNA changes that occurred during those genes' ancient history, the team showed that two mutations set the stage for hormones like estrogen, testosterone and cortisol to take on their crucial present-day roles.

    "Changes in just two letters of the genetic code in our deep evolutionary past caused a massive shift in the function of one protein and set in motion the evolution of our present-day hormonal and reproductive systems," said Joe Thornton, PhD, professor of human genetics and ecology & evolution at the University of Chicago, who led the study.

    "If those two mutations had not happened, our bodies today would have to use different mechanisms to regulate pregnancy, libido, the response to stress, kidney function, inflammation, and the development of male and female characteristics at puberty," Thornton said.

    The findings were published online June 24 in the Proceedings of the National Academy of Sciences.

    Understanding how the genetic code of a protein determines its functions would allow biochemists to better design drugs and predict the effects of mutations on disease. Thornton said the discovery shows how evolutionary analysis of proteins' histories can advance this goal, Before the group's work, it was not previously known how the various steroid receptors in modern species distinguish estrogens from other hormones.

    The team, which included researchers from the University of Oregon, Emory University and the Scripps Research Institute, studied the evolution of a family of proteins called steroid hormone receptors, which mediate the effects of hormones on reproduction, development and physiology. Without receptor proteins, these hormones cannot affect the body's cells.

    Thornton's group traced how the ancestor of the entire receptor family -- which recognized only estrogens -- evolved into descendant proteins capable of recognizing other steroid hormones, such as testosterone, progesterone and the stress hormone cortisol.

    To do so, the group used a gene "resurrection" strategy. They first inferred the genetic sequences of ancient receptor proteins, using computational methods to work their way back up the tree of life from a database of hundreds of present-day receptor sequences. They then biochemically synthesized these ancient DNA sequences and used molecular assays to determine the receptors' sensitivity to various hormones.

    Thornton's team narrowed down the time range during which the capacity to recognize non-estrogen steroids evolved, to a period about 500 million years ago, before the dawn of vertebrate animals on Earth. They then identified the most important mutations that occurred during that interval by introducing them into the reconstructed ancestral proteins. By measuring how the mutations affected the receptor's structure and function, the team could re-create ancient molecular evolution in the laboratory.

    They found that just two changes in the ancient receptor's gene sequence caused a 70,000-fold shift in preference away from estrogens toward other steroid hormones. The researchers also used biophysical techniques to identify the precise atomic-level mechanisms by which the mutations affected the protein's functions. Although only a few atoms in the protein were changed, this radically rewired the network of interactions between the receptor and the hormone, leading to a massive change in function.

    "Our findings show that new molecular functions can evolve by sudden large leaps due to a few tiny changes in the genetic code," Thornton said. He pointed out that, along with the two key changes in the receptor, additional mutations, the precise effects of which are not yet known, were necessary for the full effects of hormone signaling on the body to evolve.

    Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/eBlUGA6HrNo/130624152617.htm

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    Monday, June 24, 2013

    South Africa:Nelson Mandela in critical condition

    JOHANNESBURG (AP) ? Nelson Mandela's health has deteriorated and he is now in critical condition, the South African government said.

    President Jacob Zuma visited the 94-year-old anti-apartheid leader at a hospital Sunday evening and was informed by the medical team that Mandela's condition had become critical in the past 24 hours, the president's office said in a statement.

    "The doctors are doing everything possible to get his condition to improve and are ensuring that Madiba is well-looked after and is comfortable. He is in good hands," Zuma said in the Sunday statement, using Mandela's clan name.

    Zuma also met Graca Machel, Mandela's wife, at the hospital in Pretoria and discussed the former leader's condition, according to the statement. Zuma was accompanied on the visit by Cyril Ramaphosa, the deputy president of the country's ruling party, the African National Congress.

    Mandela was jailed for 27 years under white racist rule and released in 1990. He then played a leading role in steering the divided country from the apartheid era to democracy, becoming South Africa's first black president in all-race elections in 1994. He was hospitalized on June 8 for what the government said was a recurring lung infection.

    In Sunday's statement, Zuma also discussed the government's acknowledgement a day earlier that an ambulance carrying Mandela to the Pretoria hospital two weeks ago had engine trouble, requiring the former president to be transferred to another ambulance for his journey. Pretoria, South Africa's capital, lies about 50 km (30 miles) from Johannesburg, where Mandela has been living.

    "There were seven doctors in the convoy who were in full control of the situation throughout the period. He had expert medical care," Zuma said. "The fully equipped military ICU ambulance had a full complement of specialist medical staff including intensive care specialists and ICU nurses. The doctors also dismissed the media reports that Madiba suffered cardiac arrest. There is no truth at all in that report."

    Mandela, a Nobel Peace Prize laureate, is seen by many around the world as a symbol of reconciliation, and Zuma appealed to South Africans and the international community to pray for the ailing ex-president, his family and the medical team attending to him.

    The ruling party expressed concern about the deterioration in Mandela's health.

    "We welcome the work being done by The Presidency to ensure that South Africans and people of the world are kept informed on the state of Madiba's health," the party said. "The African National Congress joins The Presidency in calling upon all of us to keep President Mandela, his family and his medical team in our thoughts and prayers during this trying time."

    In Washington, the White House National Security Council spokeswoman noted the latest reports from the South African government about Mandela's worsening condition.

    "Our thoughts and prayers are with him, his family and the people of South Africa," said spokeswoman Caitlin Hayden.

    Prior to Zuma's statement late Sunday, reports from the government, former President Thabo Mbeki and a grandson of Mandela had indicated that the health of Mandela was improving, even though he has been in the hospital for treatment several times in recent months. In the days following his latest hospitalization, Zuma's office described his condition as serious but stable. Family members have been seen making daily visits to the hospital where Mandela is being treated.

    Mandela, who has become increasingly frail in recent years, last made a public appearance at the 2010 World Cup soccer tournament, which was hosted by South Africa. He didn't deliver an address on that occasion and was bundled against the cold in a stadium full of fans.

    On April 29, state television broadcast footage of a visit by Zuma and other leaders of the African National Congress to Mandela's home. Zuma said at the time that Mandela was in good shape, but the footage ? the first public images of Mandela in nearly a year ? showed him silent and unresponsive, even when Zuma tried to hold his hand.

    Between hospital stays in recent months, Mandela has been staying at his home in the Johannesburg neighborhood of Houghton, where he has received what the government described as "home-based high care" by a medical team. On April 6, he was discharged from a hospital after treatment for pneumonia, which included a procedure in which doctors drained fluid from his lung area.

    Mandela has been vulnerable to respiratory problems since contracting tuberculosis during his imprisonment under apartheid. Most of those years were spent on Robben Island, a forbidding outpost off the coast of Cape Town.

    Source: http://news.yahoo.com/south-africa-nelson-mandela-critical-condition-065338979.html

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    AP sources: Obama to limit carbon at power plants

    WASHINGTON (AP) ? President Barack Obama's national plan to combat climate change will include the first-ever regulations to limit carbon dioxide emissions from existing power plants, as well as increased production of renewable energy on public lands and federally assisted housing, environmental groups briefed on the plan said Monday.

    In a major speech Tuesday at Georgetown University, Obama will announce that he's directing his administration to allow enough renewables on public lands to power 6 million homes by 2020, effectively doubling the capacity from solar, wind and geothermal projects on federal property. He'll also say the U.S. will significantly expand production of renewable energy on low-income housing sites, according to five individuals briefed on the plan, who were not authorized to discuss it publicly ahead of Obama's announcement and spoke on condition of anonymity.

    The far-reaching plan marks Obama's most prominent effort yet to deliver on a major priority he laid out in his first presidential campaign and recommitted to at the start of his second term: to fight climate change in the U.S. and abroad and prepare American communities for its effects. Environmental activists have been irked that Obama's high-minded goals never materialized into a comprehensive plan.

    In taking action on his own ? none of the steps Obama will announce Tuesday require congressional approval ? Obama is also signaling he will no longer wait for lawmakers to act on climate change, and instead will seek ways to work around them.

    The lynchpin of Obama's plan, and the step activists say will have the most dramatic impact, involves limits on carbon emissions for new and existing power plants. The Obama administration has already proposed controls on new plants, but those controls have been delayed and not yet finalized. Tuesday's announcement will be the first public confirmation that Obama plans to extend carbon controls to coal-fired power plants that are currently pumping heat-trapping gases into the atmosphere.

    "This is the holy grail," said Melinda Pierce of Sierra Club, an environmental advocacy group. "That is the single biggest step he can take to help tackle carbon pollution."

    Forty percent of U.S. carbon dioxide emissions, and one-third of greenhouse gases overall, come from electric power plants, according to the U.S. Energy Information Administration, the Energy Department's statistical agency.

    Obama is expected to lay out a broad vision Tuesday, without detailed emission targets or specifics about how they will be put in place. Instead, the president will launch a process in which the Environmental Protection Agency will work with states to develop specific plans to rein in carbon emissions, with flexibility for each state's circumstances. Under one scenario envisioned by the Natural Resources Defense Council, an environmental group, states could draw on measures such as clean energy sources, carbon-trapping technology and energy efficiency to reduce the total emissions released into the air.

    Obama also will announce more aggressive steps to increase efficiency for appliances such as refrigerators and lamps, according to people briefed on the plan. Another component of Obama's proposal will involve ramping up hydropower production from existing dams.

    Heather Zichal, Obama's senior energy and climate adviser, told environmental groups Monday that Obama is working with Housing and Urban Development Secretary Shaun Donovan on a target for renewable energy to be produced at federally assisted housing projects.

    She framed the Obama's efforts in the U.S. as part of a broader, global movement to combat climate change, trumpeting the role the U.S. can play in leading other nations to stem the warming of the planet.

    Paul Bledsoe, who worked on climate issues in the Clinton White House, said Zichal renewed a pledge Obama made in in his first year in office, during global climate talks in Copenhagen, to cut U.S. carbon emissions by about 17 percent by 2020, compared to 2005 levels.

    "This is a policy fulfillment of what the president has been talking about and trying to accomplish for five years or more," said Bledsoe, now a senior fellow at the German Marshall Fund of the United States.

    One key issue Obama is not expected to address Tuesday is Keystone XL, a pipeline that would carry oil extracted from tar sands in western Canada to refineries along the Texas Gulf Coast. A concerted campaign by environmental activists to persuade Obama to nix the pipeline as a "carbon bomb" appears to have gained little traction. The oil industry has been urging the president to approve the pipeline, citing jobs and economic benefits.

    Obama raised climate change as a key second-term issue in his inaugural address in January, but has offered few details since. In his February State of the Union, he issued an ultimatum to lawmakers: "If Congress won't act soon to protect future generations, I will."

    The poor prospects for getting any major climate legislation through a Republican-controlled House were on display last week when Speaker John Boehner responded to the prospect that Obama would put forth controls on existing power plants by deeming the idea "absolutely crazy."

    "Why would you want to increase the cost of energy and kill more American jobs?" said Boehner, R-Ohio, echoing the warnings of some industry groups.

    Sidestepping Congress by using executive action doesn't guarantee Obama smooth sailing. Lawmakers could introduce legislation to thwart Obama's efforts. And the rules for existing power plants will almost certainly face legal challenges in court. The Supreme Court has upheld the EPA's authority to regulate greenhouse gases under the Clean Air Act, but how the EPA goes about that effort remains largely uncharted waters.

    Even if legal and political obstacles are overcome, it will take years for the new measures to be put in place, likely running up against the end of Obama's presidency or even beyond it. White House aides say that's one reason Obama is ensuring the process starts now, while there are still more than three years left in his final term.

    Under the process outlined in the Clean Air Act, the EPA cannot act unilaterally, but must work with states to develop the standards, said Jonas Monast, an attorney who directs the climate and energy program at Duke University. An initial proposal will be followed by a months-long public comment period before the EPA can issue final guidance to states. Then the states must create actual plans for plants within their borders, a process likely to take the better part of a year.

    Then the EPA has another four months to decide whether to approve each state's plan before the implementation period can start.

    Associated Press Writer Matthew Daly contributed to this story.

    Reach Josh Lederman on Twitter at http://twitter.com/joshledermanAP

    Source: http://news.yahoo.com/ap-sources-obama-limit-carbon-power-plants-235342639.html

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    Obama to tout economic impact of immigration

    WASHINGTON (AP) ? President Barack Obama will convene a meeting of CEOs and business leaders to tout what the White House says are the economic benefits of a landmark immigration bill.

    The afternoon meeting is scheduled just hours before the Senate holds a key test vote on a border security amendment. The measure could help the bill garner more Republican support.

    Obama is expected to highlight new estimates about the bill's impact on the national deficit. The Congressional Budget Office says the bill would reduce the deficit by about $200 billion over the next 10 years and by about $700 billion over the following decade.

    The bill would provide a pathway to citizenship for many of the 11 million people living in the U.S. illegally.

    Source: http://news.yahoo.com/obama-tout-economic-impact-immigration-073015611.html

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    Snowden says US targets included China cell phones

    HONG KONG (AP) ? A former National Security Agency contractor says that U.S. hacking targets in China included the nation's mobile-phone companies and two universities hosting extensive Internet traffic hubs in the latest allegations as Washington pushes Hong Kong to extradite the ex-contractor.

    The latest charges from Edward Snowden came in a series of reports published over the weekend by the South China Morning Post, Hong Kong's leading English-language daily. The newspaper, which appears to have access to Snowden, said Saturday he is still in Hong Kong and not in police custody.

    On Saturday, the Obama administration warned Hong Kong against dragging out the extradition of Snowden, reflecting concerns over a possible long legal battle before he ever appears in a U.S. courtroom to answer espionage charges for revealing two highly classified surveillance programs.

    A formal extradition request would also pit Beijing against Washington at a time China is trying to deflect U.S. accusations that it carries out extensive surveillance on American government and commercial operations.

    The U.S. has contacted authorities in Hong Kong to seek Snowden's extradition, the National Security Council said Saturday in a statement. The NSC advises the president on national security.

    Snowden told the South China Morning Post that "the NSA does all kinds of things like hack Chinese cellphone companies to steal all of your SMS data." It added that Snowden said he had documents to support the hacking allegations, but the report did not identify the documents. It said he spoke to the paper in a June 12 interview.

    With a population of more than 1.3 billion, China has massive cell-phone companies. China Mobile is the world's largest mobile network carrier, with 735 million subscribers, followed by China Unicom with 258 million users and China Telecom with 172 million users.

    Snowden said Tsinghua University in Beijing and Chinese University in Hong Kong, home of some of the country's major Internet traffic hubs, were targets of extensive hacking by U.S. spies this year. He said the NSA was focusing on so-called "network backbones" in China, through which enormous amounts of Internet data passes.

    Snowden is believed to be hiding in an unknown location in Hong Kong, where he has been holed up since admitting to providing information to the news media about highly classified NSA surveillance programs. He has not been seen publicly since he checked out of a Hong Kong hotel on June 10.

    The newspaper reports came after a one-page criminal complaint against Snowden was unsealed Friday in federal court, revealing he had been charged with espionage and theft.

    The Obama administration on Saturday warned Hong Kong against slow-walking his extradition, with White House national security adviser Tom Donilon saying in an interview with CBS News: "Hong Kong has been a historically good partner of the United States in law enforcement matters, and we expect them to comply with the treaty in this case."

    Some Hong Kong lawmakers have called on Beijing to intervene and instruct the Hong Kong government on how to handle the situation before his case goes through the courts, but Beijing has yet to comment. The Hong Kong government has also not commented.

    But China's state-run media have used the case to poke back at Washington after the U.S. had spent the past several months pressuring China on its international spying operations..

    A commentary published Sunday by Xinhua News Agency said Snowden's disclosures of U.S. spying activities in China have "put Washington in a really awkward situation."

    "Washington should come clean about its record first. It owes ... an explanation to China and other countries it has allegedly spied on," it said. "It has to share with the world the range, extent and intent of its clandestine hacking programs."

    Source: http://news.yahoo.com/snowden-says-us-targets-included-china-cell-phones-073119007.html

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